Topic: IL-13Rα1

Due to its association with the chromosomal region PARK12, Interleukin-13 receptor alpha 1 (IL-13Rα1) is anticipated to play a role in the pathology of Parkinson's disease (PD). Elevated IL-13 levels within the substantia nigra (SN) during chronic stress, coupled with the expression of IL-13Rα1 in dopaminergic neurons, suggest their potential involvement in neurodegenerative processes. However, the role of IL-13Rα1 in the pathological state of PD remains unclear. We investigated IL-13Rα1 expression patterns in postmortem brain tissues from PD patients and age-matched controls using western blo