Theta oscillations in the hippocampus modulate memory coding beyond just the movement state.
Mengni Wang, Li Yuan, Priscilla Ee, Junhao Zhu, Stefan Leutgeb, Jill Leutgeb · COSYNE 2025
Memory-related computations must occur across various brain states, each characterized by distinct oscillatory patterns. Theta oscillations in the hippocampal CA1 region are prominent during movement and are thought to organize network computations during active exploration, such as the virtual spatial paths formed by the sequential activity of CA1 spatial-tuning neurons, or 'place cells,' known as theta sequences. However, it remains unclear how theta supports memory during periods of immobility, when CA1 theta oscillations dissipate. To address this, we recorded laminar neural activity using
ePoster · Neuroscience