Label-free functional analysis for the characterization of iPSC-derived neural organoid development and maturation
Timm Schlegel, Johny Pires, Austin Passaro, Ben Streeter, Denise Sullivan, Parker Ellingson, Stacie Chvatal, Daniel Millard · FENS Forum 2024
The flexibility and accessibility of induced pluripotent stem cell (iPSC) technology has allowed complex human biology to be reproduced in vitro at high throughput scales. Indeed, rapid advances in stem cell technology have led to widespread adoption for the development of in vitro models of neuron electrophysiology to be used in screening applications in drug discovery and safety. Furthermore, advanced cell preparations, such as spheroids or organoids, are under intense investigation with aims toward establishing mature physiologically relevant phenotypes in vitro. The objective of this work
ePoster · Neuroscience