Understanding Bi-directional Changes and Rotation in Mitral Cell Population Codes During Repeated Odor Exposure
Xingyu Zheng, Alexei Koulakov, Saket Navlakha · COSYNE 2025
Passive odor exposure can change olfactory perception beyond simple pattern separation. Recent studies reveal that principal neurons in the mouse olfactory bulb exhibit bi-directional changes in population- level representations that depend on input similarity. Our analysis reveals the presence of a systematic drift, manifested as rotation of population vectors away from their initial representations. We explain these phenomena using a recurrent inhibition feedback model with unsupervised Hebbian learning. Our model predicts a power- law decay in mean population activity over days of odor expo
ePoster · Neuroscience