Topic: in vivo electrode recordings

Hormones regulate brain function to achieve adaptive cognitive and behavioural responses. Consequently, disruption of sex hormone signaling may underlie some aspects of sex and gender bias in psychiatric and developmental brain disorder frequency and presentation. Currently, the basis by which sex steroid hormones (e.g. estradiol) alter sensory processing and cortical function is largely unexplored, as most research focuses on impacts within the hypothalamus and limbic system. Therefore, mechanistic insight is needed to understand the fundamental organization of sex hormone action on cortical