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Topic: in vivo reprogramming

Seminar
1 seminar

In Biology and Biotechnology

Seminar · Developmental Neuroscience

Novel mechanisms of neurogenesis and neural repair

Magdalena Götz · Biomedical Center, Ludwig-Maximilians-University & Institute of Stem Cell Research, Helmholtz Center Munich, Germany

Tue, Feb 16, 2021 · 12:15 UTC

In order to re-install neurogenesis after loss of neurons upon injury or neurodegeneration, we need to understand the basic principles of neurogenesis. I will first discuss about our discovery of a novel centrosome protein (Camargo et al., 2019) and discuss unpublished work about the great diversity of interphase centrosome proteomes and their relevance for neurodevelopmental disorders. I would then present work on a master regulator of neural stem cell amplification and brain folding (Stahl et al., 2013; Esgleas et al., 2020) to proceed presenting data on utilizing some of these factors for t