Beyond BTSP: Unveiling the mechanisms for place field formation in hippocampal CA1
Mate Sumegi, Gaspar Olah, Istvan Lukacs, Judit Heredi, Martin Blazsek, Judit Makara, Zoltan Nusser · FENS Forum 2024
The rodent hippocampus is essential for spatial memory formation and navigation. Cognitive maps of each environment are created by a population of hippocampal pyramidal cells (PCs), some of which display spatially tuned firing (place cells). When an animal enters a novel environment, new spatially tuned firing (place fields: PFs) of PCs emerges. Place field formation in CA1 PCs has been proposed to rely on a well-established cellular mechanism called behavioural timescale synaptic plasticity (BTSP). During BTSP, a single occurrence of a long postsynaptic dendritic plateau potential and resulti
ePoster · Neuroscience