Effect of social choice-induced voluntary abstinence on incubation of methamphetamine craving and AMPA receptor expression in nucleus accumbens core
Claudia Marchetti, Soami F. Zenoni, Sara Pezza, Ginevra D'Ottavio, Berretta Nicola, Luisa Lo Iacono, Rossella Miele, Marco Venniro, Davide Ragozzino, Ingrid Reverte, Daniele Caprioli · FENS Forum 2024
Pre-clinical studies on drug addiction and relapse often overlooked volitional social interactions, which are of critical importance in human addiction. Recently, it has been demonstrated that social choice-based voluntary abstinence in rats attenuates the emergence of incubation of methamphetamine (Meth) craving relative to rats subjected to a forced abstinence. In the current study we investigated the molecular mechanisms by which social choice-based voluntary abstinence prevents the incubation of craving. An important mechanism driving cue-induced craving from psychostimulants in forced abs
ePoster · Neuroscience