Topic: individual axons

Adaptive myelination is the emerging concept of tuning axonal conduction velocity to the activity within specific neural circuits over time. Sound processing circuits process signals with microsecond precision: a time scale that is amenable to adjustment in length and thickness of myelin. Sound-evoked responses during postnatal development increase the activity of auditory axons and enhance myelin thickness, while sensory deprivation prevents such radial growth during development. Deprivation occurring during adulthood reduces myelin thickness. However, it is unclear if sensory stimulation adj