Topic: inhibition-stabilized networks

Cortical networks have the remarkable ability to self-assemble into dynamic regimes in which excitatory positive feedback is balanced by recurrent inhibition. This inhibition-stabilized regime is increasingly viewed as the default dynamic regime of the cortex but how it emerges in an unsupervised manner remains an open question. Theoretical work has established that four sets of weights (WE←E, WE←I, WI←E, WI←I) must obey specific relationships to produce inhibition-stabilized dynamics, but it is not known how the brain autonomously sets the values of all four weight classes to be in the suitab