Topic: inhibitory interneuron connectivity

Neuronal networks show synchronous activity or receive highly synchronous inputs during a variety of different behaviors. Deficits of synchronous activity are associated with impairment of cognition, whereas hypersynchrony can lead to epileptic seizures. Different network mechanisms for synchrony generation have been proposed and studied computationally and experimentally. One such mechanism (interneuron gamma generator, ING) relies solely on recurrent inhibitory interneuron connectivity. The number of inhibitory synapses must be sufficiently large, with the exact number depending on the other