A population of insula neurons encodes for social preference during social isolation
Christelle Glangetas, Adriane Guillaumin, Elodie Ladeveze, Anaelle Braine, Manon Gauthier, Léa Bonamy, Evelyne Doudnikoff, Thibault dhellemmes, Marc Landry, Erwan Bezard, Stephanie Caille, Anne Taupignon, Jerome Baufreton, François Georges · FENS Forum 2024
The Insula functions as a multisensory relay involved in socio-emotional processing with projections to sensory, cognitive, emotional, and motivational regions. Notably, the interhemispheric projection from the Insula to the contralateral Insula is a robust yet underexplored connection. Using viral-based tracing neuroanatomy, ex vivo and in vivo electrophysiology along with targeted circuit manipulation, we elucidated the nature and role of InsulaIns communication in social and anxiety processing in mice. In this study, we 1) characterized the anatomical and molecular profile of the InsulaIns
ePoster · Neuroscience