Inter-areal patterned microstimulation selectively drives PFC activity and behavior in a memory task
Joana Soldado Magraner,Yuki Minai,William Bishop,Matthew Smith,Byron Yu · COSYNE 2022
Thu, Mar 17, 2022
A central problem in neuroscience is to understand how areas in the brain communicate. Inputs to brain areas largely influence the intrinsic dynamics of each region, which shapes ongoing computations. Hence, characterizing how inputs drive different population responses is key to understanding how brain circuits are controlled to generate different behaviors. To this end, we developed an inter-areal patterned microstimulation (uStim) protocol that allowed us to finely manipulate the activity of a neural population in one brain area while simultaneously recording the activity of a second popula