Comparison of modulation efficiency between normal and degenerated primate retina
Yongseok Yoo, Seongkwang Cha, Yong Sook Goo · FENS Forum 2024
By applying electrical stimulation, retinal prostheses aim to bypass dysfunctional photoreceptors and directly activate retinal ganglion cells (RGCs). Therefore, effective modulation of RGCs is the key step in the development of retinal prostheses. Six cynomolgus monkeys were used: three as a control and the other three as an N-methyl-N-nitrosourea (MNU)-induced retinal degeneration model. The retinal recording was performed using the 8x8 multi-electrode array. Figure shows the electrical stimulation pulses (a), raster plots of RGC spikes (b), and the modulation efficiency score (MES) (c). The
ePoster · Neuroscience