Defining the cellular and circuit contributions of medial prefrontal cortex interneurons in associative memory
Genevieve Durocher, Paul Banks, Gareth Barker, Clair Booth, Clea Warburton, Zafar Bashir · FENS Forum 2024
Associative recognition memory, such as finding your car in a carpark, requires the quick integration of familiarity, spatial location and temporal information that is vital for episodic experience. The medial prefrontal cortex (mPFC) is a key integration hub within the associative recognition memory circuit as it receives long range excitatory inputs from the nucleus reuniens (NRe) and intermediate hippocampus (iCA1), both pathways being critical for learning. Inhibitory interneurons play essential roles in spatial and working memory function by gating signal flow and sculpting microcircuit d
ePoster · Neuroscience