Exploring axon-carrying dendrite diversity in mouse and human hippocampal interneurons
Maximilian Achilles, Tobias Herbinger, Maren Engelhardt, Christian Thome · FENS Forum 2024
Principal neurons with dendritic axon origins offer privileged pathways for information flow through the hippocampal network and between brain hemispheres. Traditionally overshadowed in research, the GABAergic interneurons play a crucial role in modulating network activity. Our research leverages genetic and immunofluorescent markers to dissect the morphological variance among inhibitory neuron subpopulations, focusing on the axon initial segments (AIS) — key sites for action potential generation. Our study captures the extensive diversity of proximal interneuron morphologies within the murine
ePoster · Neuroscience