Astrocyte activity triggers adaptive myelin plasticity and increased neuronal excitability in the somatosensory cortex following sensory deprivation
Marina Sánchez-Petidier, Elena Fernandez-López, Elena Alonso-Calviño, Claudia Miguel-Quesada, Alba Fernández-González, José Ángel Rodríguez-Alfaro, Marta Zaforas, M Concepción Serrano, Fernando de Castro, Juan Aguilar, Juliana M Rosa · FENS Forum 2024
Recent studies show that horizontal L2/3 axonal projections exhibit increased myelin segments elongation following monocular deprivation. Such adaptive myelin plasticity may improve synaptic efficacy of corticocortical connections with a possible role in mediating the reorganization of cortical maps after sensory deprivation. Here, we explored the relationship between axonal myelination and the level of cortical reorganization in distinct layers of the somatosensory cortex following central sensory deprivation. Complete thoracic spinal cord was used to induce sensory deprivation of the cortica
ePoster · Neuroscience