Stress susceptibility-dependent synaptic plasticity onto anterior cingulate cortex
Sabahaddin Taha Solakoglu, Evren Erdener, Olga Gliko, Alp Can, Uygar Sumbul, Emine Eren-Kocak · FENS Forum 2024
Aims: Investigation of differences in synaptic inputs from ventral tegmental area (VTA), ventral hippocampus (VH) and basolateral amygdala (BLA) on anterior cingulate cortex(ACC) neurons across all cortical layers between stress susceptible (SS) and stress resilient (SR) mice. Methods: Projections from VTA, VH and BLA excitatory neurons were labeled with cyan, green and yellow pre-eGRASP and ACC pyramidal neurons were labeled with post-eGRASP and TagRFP-T. Three weeks later, 10 mice were exposed to chronic social defeat stress for 10 days and on 11th day mice were divided into SS and SR groups
ePoster · Neuroscience