Persistent astrogliosis and microgliosis in the perilesional cortex after traumatic brain injury in male and female rats
Zuzanna Rauk, Zuzanna Setkowicz · FENS Forum 2024
Traumatic brain injury (TBI) is a cause of disability and a risk factor for the development of epilepsy, partially mediated by reactive gliosis. The aim of this project was to observe astroglial and microglial reactions to brain injury and identify sex differences in the process of glial scar formation.Penetrating cortical brain injury was induced on postnatal day 30 (P30) in male and female rats. The animals were perfused on P32, P38, P46, or P60. Brain tissue was sectioned and stained against glial fibrillary acidic protein (GFAP, astrocyte marker) and ionized calcium-binding adapter molecul
ePoster · Neuroscience