Topic: isoflurane anesthesia

Increasing evidence indicates that anesthetics strongly affect sensory representations and network dynamics in the thalamo-cortical circuits. By contrast, processing in the early sensory systems is thought to be mostly preserved under anesthesia, based on stimulus tuning properties like those observed in wakefulness. However, in the absence of recordings tracking the activity of the same neurons across states, there is no evidence that anesthesia preserves peripheral one-to-one sensory representations. Here, tracking for the first time the same cochlear nucleus neurons across wakefulness and i