A role for interoceptive vGluT2-expressing neurons in the jugular-nodose ganglion of the left vagus nerve in the regulation of sleep architecture and spectral composition
Najma Cherrad, Georgios Foustoukos, Alejandro Osorio-Forero, Romain Cardis, Nadine Eliasson, Yann Emmenegger, Laura Fernandez, Paul Franken, Anita Lüthi · FENS Forum 2024
When awake, we perceive stimuli from the external world. When asleep, our brain disconnects from the sensory environment. In contrast to these exteroceptive stimuli, little is known about how interoceptive stimuli are processed by the sleeping brain. The vagus nerve is a mixed sensory-motor nerve that interfaces between the autonomic periphery and the brain. We asked whether stimulating specifically vagal sensory afferents modulates sleep. All experiments are based on viral transfection of vGluT2-expressing neurons in the jugular-nodose ganglion of the left vagus nerve, in combination with pol
ePoster · Neuroscience