Effect of repeated early maternal separation on anxiety in rats during the juvenile transition period
Miroljub Popovic, Natalija Popovic, Antonia Alonso, Ramon Pla, Bruno Ribeiro Do-Couto, Kuei Y. Tseng, Jose Luis Ferran · FENS Forum 2024
Early life stress plays a crucial role in modulation of physiological and psychological processes during ontogenesis. One of the stressors that might contribute to development of mental disorders is maternal separation (MS). The purpose of this study was to evaluate the effect of MS on anxiety of rats during the juvenile transition period. The experiments were performed on both female and male Sprague Dawley rats. The early life repeated MS was proceeded from 11 to 20 postnatal days (PND) in duration of 4 h per day during active phase of circadian rhythm (from ZT15 until ZT19, Zeitgeber time-Z
ePoster · Neuroscience