Sex dimorphic role of NMDA receptors in hippocampal-dependent spatial memory and plasticity during juvenility
Nisha Rajan Narattil, Mouna Maroun · FENS Forum 2024
Juvenility (early life) is the crucial stage of neurodevelopment, as the alterations made during this time have been linked to long-term effects on cognition. The brain undergoes significant remodelling involving dendritic arborization, synaptogenesis and neuron proliferation within and between areas, particularly in the hippocampus, which plays a vital role in spatial memory processing. Spatial memory processing ability continues to develop alongside hippocampal maturation particularly before puberty. The N-methyl-d-aspartate (NMDA) type of glutamate receptor channel is essential for activity
ePoster · Neuroscience