ePoster · Computational Neuroscience
Neuronal spike generation via a homoclinic orbit bifurcation increases irregularity and chaos in balanced networks
Moritz Drangmeister, Rainer Engelken, Jan-Hendrik Schleimer, Susanne Schreiber · Bernstein Conference 2024
Recent theoretical models and experimental data have revealed that many neurons can exhibit homoclinic (HOM) spike-onset bifurcations by tuning variables like temperature, extracellular ion concentrations, or channel expression levels within the physiologically plausible range. In this HOM regime, spike trains have burst-like irregular firing induced by stochastic switches between attractors. While single-neuron bifurcations leading to HOM dynamics are well-studied (Hesse et al., 2022; Contreras et al., 2021; Hürkey et al., 2023; Schleimer et al., 2021; Niemeyer et al., 2021), their impact on