Mapping neural recovery: Comparative molecular insights into spinal cord injury across species
Nicola Regazzi, Claudia Kathe, Thomas H. Hutson, Matthieu Gautier, Alan Y. Teo, Katia Galan, Simon Borgognon, Charles F. V. Latchoumane, Sandra Braz, Joana Nogueira-Rodrigues, Jeff M. Gidday, Matthew Lawrence, Monica M. Sousa, Quentin Barraud, Mark A. Anderson, Michael Skinnider, Jocelyne Bloch, Grégoire Courtine, Jordan Squair · FENS Forum 2024
A spinal cord injury (SCI) triggers a multifaceted series of secondary injuries, involving inflammation, cell death, demyelination, and scar formation. How the individual types and subtypes of cells of the central nervous system coordinate to mediate this response remains unclear. While much of our current knowledge is derived from rodents, therapies effective in these models have not translated successfully to clinical trials. Understanding molecular responses across species—lower vertebrates, non-primate mammals, and primates—is crucial for formulating effective human treatments. We aim to u
ePoster · Neuroscience