Topic: Lactobacillus sakei

Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by movement disorders. The main characteristic of PD is the loss or degeneration of dopaminergic neurons in the substantia nigra. The gut microbiota is now recognized as a potential participant in the pathogenesis of PD. This study aims to investigate the effects of Lactobacillus sakei (Ls) on the gut-brain axis and explore the underlying molecular mechanism using a PD model. Probiotics were orally administered for four weeks after MPTP injection. The study observed that Ls significantly improved movement, includi