Topic: lateral central amygdala

Neuromodulators like dopamine are critical regulators of associative learning. Indeed, dopaminergic neurons in the dorsal tegmental area interact with the lateral central amygdala (CEl) circuitry involved in fear behavior. Thus, fear learning modulates the microcircuit of the CEl composed of somatostatin-positive (SST+) and protein kinase C-positive (PKCδ+) neurons. During this process, dopamine 1 receptor (D1R) activation enables LTP induction in SST+ CEl neurons (Groessl et al. 2018, Nat Neurosci 21:952-962).In fact, a detailed analysis of dopaminergic cellular effects on synaptic transmissi