Topic: lateral hypothalamus GABAergic neurons

Home drives various emotionally charged behaviors, such as relaxation and territorial defense. However, how ‘home’ information is organized in the brain to drive the diverse even conflict-affective behaviors remains elusive. Here we found that home bedding carried sufficient home information as it could relieve aversion in fear or anxiety contexts, trigger defensive behaviors towards intruders, and promote mating behaviors in mice. Representations of such home information in diversified behavioral contexts were all mapped to the lateral hypothalamus GABAergic neurons (LHGABA). Inhibiting LHGAB