Linking sensory stimuli to avoidance behavior: Investigating the role of adaptive cell populations in prefrontal cortex
Anh Duong Vo, Benjamin Ehret, Roman Boehringer, Elisabeth Abs, Benjamin F. Grewe · FENS Forum 2024
The medial prefrontal cortex (mPFC) plays a crucial role in integrating sensory input for learned stimulus-response associations. However, the link between sensory stimuli and changing behavioral relevance remains poorly understood. We studied how sensory stimuli and neural representations of associated behaviors emerge in mPFC during avoidance learning.We performed mobile population calcium imaging in mice mPFC during an active avoidance task. In this task, mice learned to avoid an aversive foot shock associated with conditioned tone stimuli CS1 and CS2. CS1 was first followed by the shock in
ePoster · Neuroscience