ePoster · Neuroscience
Impacts of ciproxifan on the tissue of the hippocampus in rats with cerebral ischemia-reperfusion
Bengi Yegin, Dilek Burukoglu Donmez, Semih Oz, Sule Aydin · FENS Forum 2024
Cerebral ischemia is the result of reduced or interrupted blood flow to the brain. Cerebral ischemia is reversible or irreversible in the neurons of the affected area, and subsequent free radical damage can be exacerbated by reperfusion. Ciproxifan is used to study the involvement of histaminergic neurons in different phases such as wakefulness and cognition. We wanted to find out whether ciproxifan has a protective effect on the hippocampus of rats with cerebral ischemia-reperfusion injury.A total of 32 adult male rats were used for the experiment. Four cages were formed with randomly selecte