Meningeal neural progenitors respond to central nervous system autoimmune disease and interact with immune cells
Francesca Ciarpella, Stefania Zorzin, Celia Lerma Martin, Alessandro Bani, Barbara Rossi, Silvia Dusi, Benedetta Lucidi, Andrea Corsi, Sissi Dolci, Bruno Miguel Dos Santos Lima, Nicola Lopez, Lucas Schirmer, Francesco Bifari, Gabriela Constantin, Ilaria Decimo · FENS Forum 2024
Meninges are a system of three-layered membranes which envelop the Central Nervous System (CNS) at each level of its organization, acting as a protective barrier. Beside this acknowledged role, meninges have emerged as complex structures able to sense, integrate and respond to CNS, external stimuli and injury. Recently, meninges have been suggested as a novel neurogenic niche hosting neural progenitors (NPCs) which can migrate and integrate into the brain cortex. However, their contribution to brain autoimmune disease is still unknown. We aimed to assess the role of meningeal neural progenitor
ePoster · Neuroscience