Facilitating memory consolidation through light exercise: The role of the coeruleo-hippocampal dopaminergic pathway
Taichi Hiraga, Toshiaki Hata, Shingo Soya, Joshua Johansen, Tomonori Takeuchi, Masahiro Okamoto, Hideaki Soya · FENS Forum 2024
Physical exercise benefits the dorsal hippocampus (dHPC) and promotes learning and memory. We have focused on light exercise (LEX) and have revealed that this accessible form of exercise can effectively increase hippocampal activity and enhance memory performance. However, the circuit mechanism underlying this benefit remains largely undetermined. Our recent findings demonstrate that LEX can stimulate tyrosine hydroxylase-positive (TH+) neurons in the locus coeruleus (LC) and the ventral tegmental area (VTA), and increase noradrenaline (NA) and dopamine (DA) release in the dHPC. This raises th
ePoster · Neuroscience