Next-generation head-mounted microscopes for large-scale neural recordings
Joe Scherrer, Galen Lynch, Jie Zhang, Michale Fee · COSYNE 2023
Miniature head-mounted microscopes have enabled in vivo optical measurements of neural activity in freely moving animals, allowing neuroscientists to study the neural basis of behaviors that are difficult to recapitulate in head-fixed preparations like social interaction and navigation. Existing head-mounted microscopes for small animals are limited to small fields of view (< 1mm2), which limit the number of neurons that can be recorded simultaneously to at most several hundred. However, understanding how behavior is controlled by large neural populations across brain regions requires simul
Sat, Mar 11, 2023