Constrained Multi-Regional Recurrent Neural Networks Elucidate Distributed Motor Timing Dynamics
John Lazzari, Zidan Yang, Shreya Saxena, Hidehiko Inagaki · COSYNE 2025
The ability to flexibly time movements is crucial for behavior. The motor cortex, basal ganglia, and thalamus form a multiregional neural network, known as the cortico-basal ganglia thalamocortical (CBGTC) loop, which controls various aspects of motor behaviors, including the timing of actions [1]. For example, in mice performing a delayed licking task, average activity in the striatum and cortex ramp up to a threshold for executing a lick [2]. However, the distinct contributions from different cell types and regions within the CBGTC loop remain largely unknown due to the similarity in their r
ePoster · Neuroscience