A single cell atlas to unveil the diversity of mouse cerebellar astrocytes: Insights into their molecular identities, development, and functions
Annalisa Buffo, Annalisa Cerrato, Giacomo Turrini, Ludovic Telley · FENS Forum 2024
Astrocyte heterogeneity is essential for understanding the development and function of the central nervous system. While the main types of cerebellar astrocytes can be identified based on their morphology and location, we have limited knowledge about their molecular profile, development, and functions. Furthermore, whether the existing classification truly reflects the full extent of cerebellar astrocyte heterogeneity remains unclear. Single-cell RNA sequencing and spatial transcriptomics performed on both postnatal and adult mouse cerebella unveiled the transcriptome of established astrocyte
ePoster · Neuroscience