Topic: long-range horizontal projections

In ferret visual cortex, spontaneous activity prior to eye-opening is organized into large-scale, modular patterns in the absence of long-range horizontal projections. This correlated activity reveals endogenous networks that predict aspects of future orientation selectivity [1]. Previous modelling works have shown that the long-range correlations observed in these networks can arise from purely locally connected neurons through multi-synaptic interactions [1][2]. Here we seek to explicitly map the structure of cortical lateral interactions through localized perturbations in vivo. We first con