Topic: LoopRNATM ISH technology

Aim: Over the past decade, our understanding of the transcriptional landscape in the brain has undergone a dogma-challenging expansion, revealing the intricate role of non-protein-coding RNAs (ncRNAs) in neural function, development, and disease. A large number of ncRNAs have been discovered and implicated in molecular regulatory processes involved in neural homeostasis and activity and seem to play crucial roles in neurodegenerative disorders and cancer. This study aims to assess the efficacy of in situ hybridization (ISH) in profiling long non-coding RNAs (lncRNAs) and circular RNAs (circRNA