Pericytes are involved in hypertension-induced cognitive decline
Selin Selvi-Sapancı, Feride Demirhan, Fatmanur Akpunar, Busra Tekirdaglı, Esra Ozkan, Yasemin Gursoy-Ozdemir · FENS Forum 2024
AIM: Hypertension is known to impair microcirculation in the brain, leading to cerebral small vessel disease (CSVD), which correlates strongly with cognitive impairment. Studies have shown a high prevalence of hypertension-related cranial MRI lesions, including arteriosclerosis and various forms of brain damage. Pericytes, a component of the neurovascular unit, are implicated in controlling blood flow and have been linked to Alzheimer's disease pathology, but their role in hypertension-related microcirculation disorders and vascular dementia has not been extensively studied. The study aims to
ePoster · Neuroscience