Characterization of a hippocampal model of epileptiform activity
Pablo Reyes Velasquez, Lucia Sangroniz-Beltrán, Juan Cobos, Lorena Ruiz-Clavijo, Nicolas Landgraf, Jon Egaña-Huguet, María Ceprian, Diego Mateos, Pavel Rueda, Raimundo Baéz-Mendoza, Juan Manuel Encinas-Perez, Edgar Soria-Gomez · FENS Forum 2024
Epileptiform activity (EA) comprises abnormal excessive neuronal discharges (spikes and sharp waves) detectable by electroencephalogram. The term EA originates from epilepsy research, where interictal EA appears in EEG between seizures. Importantly, EA occurs not only in epilepsy but also in various pathologies, possibly contributing to cognitive impairment. EA has been observed in neurodegenerative disorders like Alzheimer's and Parkinson's diseases. However, a direct causal link between EA and cognitive impairment remains elusive. A significant issue is the lack of a pure EA model for invest
ePoster · Neuroscience