Topic: low-intensity ultrasound

Focal brain stimulation effectively treats intractable epilepsy and severe depression, which are difficult to treat with drugs. Neuromodulation is a technique that uses external devices to stimulate the brain and modulate neural function, among which ultrasound is highly bio-permeable and can penetrate deep into the brain non-invasively. Stimulation with patterned low-intensity ultrasound can induce sustained inhibition of neural activity in humans and animals, with potential implications for research and therapeutics. Although mechanosensitive channels are involved, the cellular and molecular