Arousal dynamics: diverse measurements of a universal manifold
Ryan Raut, Zachary Rosenthal, Xiaodan Wang, Adam Bauer, Steven Brunton, Bing Brunton, J. Nathan Kutz · COSYNE 2023
Recent findings from awake, behaving animals lead us to hypothesize the existence of an underlying dynamical process whose manifestations are observed across diverse neural, physiological and behavioral measurements. Our ability to construct nonlinear mappings between such measurements (here, pupillometry and widefield calcium imaging) from a latent, low-rank representation of their dynamics provides strong support for this hypothesis. Specifically, we introduce an integrative theoretical framework that casts arousal as a dynamical process unfolding along a low-dimensional manifold that segreg
Sun, Mar 12, 2023