Topic: M2→AC projection neurons

The ability to flexibly respond to sensory cues in dynamic environments is essential to adaptive auditory-guided behaviors such as navigation and communication. How do neural circuits flexibly gate sensory information to select appropriate behavioral strategies based on sensory input and context? Auditory neural responses during behavior are diverse, ranging from highly-reliable ‘classical’ responses (i.e. robust, frequency-tuned cells) to irregular or seemingly random ‘non-classically responsive’ firing patterns (i.e., nominally non-responsive cells) that fail to demonstrate any significant t