Light modulates central oxytocin and social memory via a retina-to-supraoptic nucleus circuit
Yu-Fan Huang, Po-Yu Liao, Jo-Hsien Yu, Shih-Kuo Chen · FENS Forum 2024
In the realm of memory, environmental lighting exerts significant influence, impacting various cognitive processes such as fear and object memory. Within this context, our laboratory has previously conducted research demonstrating that brief exposure to light adversely affects social recognition memory (SRM) in mice. Specifically, we found that light exposure hampers the activity of oxytocin neurons located in the supraoptic nucleus (SON) through a pathway involving M1 SON-projecting intrinsically photosensitive retinal ganglion cells (ipRGCs) and GABAergic neurons situated in the perinuclear
ePoster · Neuroscience