Topic: mean-driven regime

A neuron’s input-output function is a central component of network dynamics and is commonly understood in terms of two fundamental operating regimes: 1) the mean-driven regime where the mean input drives regular and frequent firing, and 2) the fluctuation-driven regime where input fluctuations drive responses at relatively low firing frequency but with variable intervals. Active dendrites are expected to profoundly influence the input-output function by either controlling gain modulation or through the additive modulation by dendritic inputs that have been transformed nonlinearly as in an arti