Topic: medial temporal lobe memory system

The perirhinal and parahippocampal cortices are key components of the medial temporal lobe memory system and essential for the processing of spatial and declarative memory. In humans, major changes in declarative memory capacities occur within the first seven years of life, but until recently, the neurobiological substrates underlying these changes remained hypothetical. Previous studies have shown that distinct regions, layers and cells of the hippocampus and entorhinal cortex exhibit different profiles of structural and molecular development during early postnatal life. Accordingly, the diff