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Topic: membrane microarrays

ePoster
1 ePoster

In Neuroscience

Multiparametric analysis of metabolic and oxidative stress on lipids and proteins in microarray printed astrocytic and neuronal lipid raft membranes

Laura Sánchez-Sánchez, Roberto Fernandez, Egoitz Astigarraga, María Dolores Ganfornina Álvarez, Gabriel Barreda Gómez · FENS Forum 2024

Lipid rafts are liquid-ordered domains where specific enzymes and receptors are located. These membrane platforms play crucial roles in a variety of signaling pathways. Thus, alterations in the lipid environment, such as those elicited by oxidative stress, can lead to important functional disruptions in membrane proteins. Cell membrane microarrays has emerged as a powerful methodology for the study of both lipids and membrane proteins, as they preserved native protein structure and lipid environment. Based on this technology, we developed membrane microarrays with different lipid raft preparat

ePoster · Neuroscience