A low-dimensional signature of global brain state in the superior colliculus of the macaque
Richard Johnston & Matthew Smith · COSYNE 2023
Recent work has shown that global signals related to arousal are embedded in the population activity of cortical neurons. In mice, slow fluctuations in neural activity are correlated with whisking and locomotion, while in monkeys a similar pattern has been identified (termed “slow drift”) that is: 1) present in visual/prefrontal cortices; 2) correlated with pupil size; and 3) associated with performance on cognitive tasks. These results demonstrate that changes in brain state are represented in the coordinated activity of cortical neurons. However, it is unknown if these fluctuations are also
Sat, Mar 11, 2023