Topic: memory impairments

The meninges are a protective and nutritious tissue that surrounds the central nervous system (CNS) and supports the brain. Recent data, including from our team, have revealed that the meninges contain a myriad of immune cells, such as meningeal macrophages (MM). Interestingly, the meninges penetrate the brain parenchyma and contact sub-structures such as the hippocampus, which is one of the main neurogenic niches. This strategic position of the meninges and thus MM raised the hypothesis that these cells could play a role in hippocampal neonatal neurogenesis. To address this question, we used