Topic: memory reprocessing

Memory consolidation involves the spontaneous activity of multiple brain areas potentially supporting the reprocessing of novel and more remote memories. Traditionally, study of these phenomena has focused on a handful of brain areas, such as hippocampus and the prefrontal cortex. Here, we are currently investigating how wider cortical networks support memory reprocessing. We are doing so by combining optical (wide-field) voltage imaging with laminarly-resolved hippocampal electrophysiology in mice, to get a large-scale view of the brain activity. Animals perform two virtual reality memory tas