Topic: mesocorticolimbic dopamine system

Binge eating disorder (BED) and obesity are complex diseases characterized by maladaptive feeding behaviors, particularly towards palatable foods. The mesocorticolimbic dopamine system, also known as the "reward system," plays a crucial role in hedonic food intake and is implicated in both disorders. The endocannabinoid system (ECS), present in the reward system, regulates feeding behaviors but its involvement in BED and obesity is not fully elucidated. Recent research suggests its significant role in feeding behaviors, especially in addictive-like eating behaviors, prompting the hypothesis of